One of the aims in the AI research, is to understand the principles and mechanisms of intelligence in the human brain. Definitely the brain is a neurocontroller, a collection of neurons which learn to output the right actions or decisions over time. This paper describes recent neurocontrol designs which are considered the state-of-the-art for intelligent control and their plausibility as models of the human brain.

While Orthodox Christianity does not find explicit statements about the morality of prolonging life in the usual doctrinal sources, the Scriptures and the Fathers of the Church, there are elements in Tradition which bear upon the issue. These include Orthodox spirituality's emphasis on the “wholeness” of the human person, its liturgical and synergistic view of human life, and its understanding of our moral ambiguity as fallen human beings in a fallen world. This last point, in particular, means that we do (...) not usually have a clear choice between right and wrong, and that we cannot always trust ourselves to know which choice is the right, or even the better one. Therefore, we must always approach decisions about death and dying with humility and in a spirit of repentance, aware of the imperfection of all we do and trusting in the mercy of God. (shrink)

Contentious relations between Türkiye and Greece can be traced back centuries to conflicts such as Ottoman Turks conquering Istanbul which was the centre of the Byzantine Empire in 1453 and the 182...

This study explores consumer expectations and attitudes related to gender-based price discrimination. Although much research has focused on pay inequalities and gender diversity, considerably less attention has been focused on situations in which men and women are charged different prices based on gender. In two studies, expectations and attitudes toward gender-based price discrimination are examined. In Study 1, two scenarios related to prices at hair salon and dry cleaning services were manipulated to measure expectations and attitudes toward gender-based price discrimination. (...) We found that the nature of the service results in expectations of price differences between men and women. We also found men expect gender-based pricing more than women. In Study 2, qualitative research was conducted to reveal the cognitions that men and women experience when exposed to gender-based price discrimination. (shrink)

Calculation is omnipresent in the current pandemic. And yet, Continental philosophers never talk about calculation: it seems to be the c** of philosophy. Why is that so? Has it always been like that?

The article comments on the epistemological foundations of medieval Arabic science and philosophy, as presented in five earlier communications, and attempts to draw some guidelines for the study of its social history. At the very beginning the notion of "Islam" is discounted as a meaningful explanatory category for historical investigation. A first part then looks at the applied sciences and notes three major characteristics of their epistemological approach: they were functionalist and based on experience and observation. The second part looks (...) at the theoretical sciences and notes that their epistemology was based on geometrical as well as (b) syllogistic modes of proof, and that the particular approach of scientists and philosophers was determined by (c) whether the motivations of each were scientific or non-scientific (e.g., religious, dogmatic, eristic, etc.). A third part concludes that for medieval Arabic-writing scholars with a scientific motivation the epistemological bases of their work were common to scientists to all cultures, and that the causes of advance or decline of Arabic science and philosophy have to be sought in social factors. In this regard three factors are presented as instrumental: (a) the level of patronage and wealth in any given society within the medieval Islamic world, (b) the cultural attitude of ideological laissezfaire in Sunni Islam which neither imposed nor adopted authoritative solutions in scientific and philosophical issues, and (c) the temporal and local specificity of scientific activity that makes the social contextualization of each science necessary in historical work. (shrink)

The subject of this article is the concept of natural liberation in classical Sāṃkhya. On the basis of the Sāṃkhyakārikā by Īśvarakṛṣṇa and its traditional commentaries, I will attempt to demonstrate that liberation from suffering in Sāṃkhya is not the result of rational inquiry—the prevailing view among contemporary scholars. The Sāṃkhya does not necessarily prescribe yogic practice as argued by other scholars. Instead, I will defend a position expressed by K.C. Bhattacharyya and Frank R. Podgorski, according to which liberation in (...) classical Sāṃkhya is a natural and spontaneous process of suffering transforming into its own cure. I will argue that although traditional authorities may disagree over the form the liberating process takes on the phenomenal level, there is a general agreement that the natural forces are the primary drives and agents of liberation. (shrink)

Based on an analysis of double hermeneutics in the human sciences, a distinction between a weak and a strong rhetorical analysis of human-scientific research is introduced, taking account of the self-reflective character of hermeneutic interpretation. The paper argues that there are three hermeneutic topics in the research process for human-scientific experience, which are associated with applying specific rhetorical tools. The three topics are described under the following rubrics: (a) bridging the gap between experience-near and experience-distant concepts; (b) achieving integrity of (...) the cultural objects dispersed in different interpretive strategies; and (c) taking into consideration that an important task of hermeneutic interpretation in human-scientific research is to give an account of the object's immanent narrative coherence. The paper is written in the conviction that a kind of re-methodologization of philosophical hermeneutics which does not rehabilitate epistemological foundationalism can provide a new philosophical identity to the human sciences. (shrink)

At Statesman (Plt.) 291a–c and 303c–d, Plato compares the so-called statesmen of all existing constitutions to a motley crew of lions, centaurs, satyrs, and other beasts, and the entire section of the Statesman devoted to law and constitutions (291c–303c) to a satyr-play of sorts. This paper argues that these thought-provoking images are best understood as literary devices which, in addition to other dramatic elements in the Theaetetus and Sophist, help to bolster the unity of the Theaetetus-Sophist-Statesman trilogy and its apologetic (...) agenda concerning Socrates. (shrink)

The paper examines the sense in which Gianni Vattimo’s story of a long goodbye of modernity along with an interminable weakening of Being inaugurates a leftist philosophico-political project. The hermeneutics of “weak thought” is criticized for (a) its ambiguous concept of interpretation; (b) its way of integrating proceduralism in post-metaphysical philosophizing; and (c) the unhappy marriage it promotes between nihilism and emancipation. Finally, a philosophico-political version of hermeneutic ontology based on the idea of situated transcendence is suggested as an alternative (...) to Vattimo’s nihilistic socialism. (shrink)

J’ai découvert l’oeuvre de Jacques Derrida quand j’étais étudiant dans un département de philosophie analytique. L’un de mes professeurs – un spécialiste du positivisme – parlait d’un philosophe français comme du « plus grand logicien du vingtième siècle ». Ce philosophe français, c’était Derrida. -/- J’aimerais prendre au sérieux cette assertion, en la mettant à l’épreuve d’une rencontre entre la conception philosophique occidentale de la liberté et la logique derridienne. Rencontre que je propose de mettre en scène sous la forme (...) de deux instantanés. (shrink)

Taking user’s role and features as milestones for an approach on scientific representation has become a growing trend. We shall investigate the implications that pragmatics bring in the relevant debate. Proponents of pragmatic approaches support that questions such as ‘how an object represents another’ or ‘which features of a certain object represent the target of the representation and in what way’ can be answered only within the given context of representation’s use. Thus, attention is drawn to the intentionality of the (...) representation, in contrast to the semantic tradition, according to which the representational function is based on morphic relations between the representation and the represented object. Given that scientific representations surrogate objects and phenomena in our studies, they should reproduce aspects, relations and interactions of them, possessing the appropriate features. Therefore, we support that user’s intention is not enough to build the representational relation on it. We claim that a) a sustainable and successful theory of scientific representations cannot be grounded on pragmatics b) pragmatic approaches undermine the objectivity of the knowledge inferred by representations c) the important role of the cognizing subject in a theory of scientific representation can be rescued without the burden coming with pragmatic approaches. (shrink)

The excavation of a ceramic workshop in the region of the ancient town of Corfu brought to light many elements connected with ceramic production. The workshop was in operation from the 5th to the 3rd c. BC. Among the remains of vases and other objects was a large number of small objects, chiefly of bronze and bone. A group of thirty-seven objects was identified, which could hâve been used by the potters and painters of the workshop as tools. A comparison (...) of these tools with those employed by contemporary potters produced interesting facts about their utilisation. Lastly, the places where the tools were found made it possible to clarify precisely the way in which the ancient workshop operated. (shrink)

Même si bon nombre de ses travaux ont porté sur l’interprétation des mythes grecs fondateurs, Vernant a consacré la première partie de sa carrière à l’étude de la naissance de la polis et de la démocratie grecques. Contre l’idée d’un surgissement miraculeux de la Raison en Ionie au VI e siècle avant notre ère, Vernant a montré ce que la conception grecque de la rationalité hérite du monde homérique mais surtout ce qu’elle doit aux structures sociales et politiques de la (...) polis démocratique. Mais les travaux de Vernant font plus qu’établir l’acte de naissance d’une forme particulière de rationalité « fille de la cité » : ils touchent au cœur du problème plus général des rapports entre raison et démocratie. (shrink)

Activating Transcription Factor-2 is a sequence-specific DNA-binding protein that belongs to the bZIP family of proteins and plays diverse roles in the mammalian cells. In response to stress stimuli, it activates a variety of gene targets including cyclin A, cyclin D and c-jun, which are involved in oncogenesis in various tissue types. ATF-2 expression has been correlated with maintenance of a cancer cell phenotype. However, other studies demonstrate an antiproliferative or apoptotic role for ATF-2. In this review, we summarize the (...) signaling pathways that activate ATF-2, as well as its downstream targets. We examine the role of ATF-2 in carcinogenesis with respect to other bZIP proteins, using data from studies in human cancer cell lines, human tumours and mouse models, and we propose a potential model for its function in carcinogenesis, as well as a theoretical basis for its utility in anticancer drug design. (shrink)

Dans cet ouvrage, Dimitri El Murr reprend la question posée par Platon – et, depuis, à l’horizon de toutes nos institutions politiques –, des rapports entre savoir et pouvoir, en réexaminant la portée et les analyses du Politique, contribution majeure de la réflexion platonicienne à ce problème. Que le savoir soit en lui-même un pouvoir, c’est ce que Socrate soutenait dans le Protagoras et le Gorgias, mais ce pouvoir restait celui de l’âme sur elle-même et sa conduite. À partir (...) de la Républiq... (shrink)

The periodic table of the elements is one of the most powerful icons in science: a single document that captures the essence of chemistry in an elegant pattern. Indeed, nothing quite like it exists in biology or physics, or any other branch of science, for that matter. One sees periodic tables everywhere: in industrial labs, workshops, academic labs, and of course, lecture halls. It is sometimes said that chemistry has no deep ideas, unlike physics, which can boast quantum mechanics and (...) relativity, and biology, which has produced the theory of evolution. This view is mistaken, however, since there are in fact two big ideas in chemistry. They are chemical periodicity and chemical bonding, and they are deeply interconnected. The observation that certain elements prefer to combine with specific kinds of elements prompted early chemists to classify the elements in tables of chemical affinity. Later these tables would lead, somewhat indirectly, to the discovery of the periodic system, perhaps the biggest idea in the whole of chemistry. Indeed, periodic tables arose partly through the attempts by Dimitri Mendeleev and numerous others to make sense of the way in which particular elements enter into chemical bonding. (shrink)

Avant de s'emparer de ce qu'elle sait, ou croit savoir, pour élaborer des théories, l'intelligence, lorsqu'elle s'éveille, est d'abord frappée par des évidences qui s'imposent à elle. A ce moment-là, l'intelligence est saisie, donc elle sort d'elle-même en s'ouvrant à la réalité, et elle en est consciente. Bref, elle tient une vérité. En même temps, ces lumières n'expliquent pas tout ;par conséquent, elles suscitent, tout naturellement, des questions. De là va naître ce que, à la suite de saint Thomas d'Aquin, (...) on a appelé :" la philosophie naturelle de l'esprit humain " qui, seule, peut nous délivrer, définitivement et objectivement, du relativisme et du vide, donc du désespoir. Point de départ de ces réflexions, la découverte de l'être et de sa nécessité dans l'évidence, intellectuelle qu'il y a quelque chose de bon et de beau en face de moi. A partir de là on discerne, certes, l'Erre perfection pure, mais surtout l'immatérialité de la connaissance, sans laquelle l'amour perd toute sa profondeur, et qui est le fondement de notre ressemblance à Dieu. C'est dire assez à quel point la foi suppose cette philosophie. Ces pages veulent s'adresser aux non-spécialistes, tout en essayant de répondre aux exigences de rigueur d'un esprit critique. Exercice difficile, mais à la hauteur de l'enjeu, exprimé de façon saisissante par Dimitri Karamazov :"Je suis fort peu instruit, frère, mais j'ai beaucoup songé à ces choses. Que de mystères accablent l'homme! Pénètre-les et reviens intact. ". (shrink)

Sahip olduğu akademik imkânların ve başta İngilizce olmak üzere birçok dilde uluslararası yayınların çokluğu nedeniyle Amerika Birleşik Devletleri’ndeki İslam çalışmaları yoğun, üretken ve dünya genelinde ilgiyle takip edilen bir alandır. Ancak Batı’daki üniversitelerin genelinde olduğu gibi Amerikan üniversitelerinde de İslam felsefesi/tarihi çalışmaları oldukça zayıftır. Bu makalede öncelikle geçmişten günümüze İslam çalışmalarının ABD’deki durumu tasviri bir metotla ortaya konulmakta ve İslam Felsefesinin ABD’deki İslam çalışmaları içerisindeki zayıf konumu sorgulanmaktadır. İkinci olarak Post-Oryantalist süreçte İslam Felsefesi çalışmalarında öne çıkan isimler ve çalışmaları değerlendirilmektedir. (...) Sonuç olarak ABD üniversite sisteminin genel yapısının gereği olarak İslam Felsefesi çalışmaları nicelik bakımından Avrupa ve İslam coğrafyasından daha zayıf olduğu görülmektedir. Bu durumu iki şekilde açıklamak mümkündür. Birincisi alanın Amerikan devlet felsefesinin temel ilkesi olan bilgi-güç hedefi ve alanın politik çıkarlarıyla ilişkisinin zayıflığıdır. Bu durum Post-Oryantalist eğilimin arka planını da oluşturmaktadır. İkincisi ise fenomenolojist yönteme olan ilginin artması ve Amerikan yükseköğretim sisteminde hâkim olan kozmopolitanizm ve interdisiplinerci yaklaşımlardır.Özet: Dünyanın önde gelen üniversitelerinde İslam çalışmaları ve bu çalışmalar içerisinde yer alan İslam felsefesi çalışmalarının önemli bir akademik ilgi alanı olduğu görülmektedir. Bu ilgi ABD’de de yaklaşık 150 yıllık bir geçmişe sahiptir. Son yıllarda Amerika Birleşik Devletleri’nde İslam çalışmalarında sadece ciddi bir artış değil aynı zamanda çeşitlenme de söz konusu olmuştur. ABD’deki İslam çalışmaları ve özelde İslam felsefesi çalışmalarının durumunu birlikte ele alan akademik araştırmalar ise henüz bulunmamaktadır. Son gelişmeleri de dikkate alarak alanla ilgili araştırmaların sürdürülmesi ve İslam felsefesi çalışmalarının da noksan bırakılan izinin sürülmesi gerekmektedir. Bu noktadan hareketle bu makale çalışması, üniversite müfredatlarıyla ilgili araştırmalar, web taramaları ve yazılı materyaller üzerinden gerçekleştirilecek ve ilgili kitaplar, makaleler ve diğer kaynaklar taranarak konu hakkında deskriptif bilgiler sunulacaktır. Bu yöntemin tercih edilme nedeni derinlemesine bir araştırmadan daha çok genel resmi ortaya koymak ve mevcut durum hakkında bilgi vermektir. Sahanın genişliği ve kaynakların çeşitliliği ve konunun daha özel ve yoğun bir çalışma gerektiren yapısı nedeniyle diğer yöntemler tercih edilmemiştir Çalışma iki ana başlıktan oluşmaktadır. Birincisi ABD’deki İslam çalışmalarının konumu ile ilgilidir. Bu başlık altında 18. yüzyıldan itibaren İslam çalışmalarının ABD’deki seyri hakkında bilgi verilmekte ve İslam çalışmalarının günümüzdeki konumu detaylandırılmaktadır. İkinci başlık İslam Felsefesi çalışmalarının İslam çalışmaları içerisindeki ve ABD akademilerindeki konumuyla ilgilidir. Bu başlık altında İslam Felsefesi çalışmalarının geçmişten günümüze kadar gelinen süreçte geçirdiği evreler tasvir edilmekte ve bazı isimlerin ve eserlerinin değerlendirmesi yapılmaktır. İncelemeler sonucunda ABD’deki İslam çalışmalarının geçmişinin yaklaşık 150 yıla tekabül etmesine rağmen yeterli seviyeye ulaşmadığı görüldü. Hâlbuki sahip olduğu Müslüman nüfus, akademik imkânlar ve başta İngilizce olmak üzere birçok dilde uluslararası yayınların çokluğu nedeniyle ABD’deki İslam çalışmalarının beklenenden daha yoğun, üretken olması beklenirdi. Ancak buna rağmen Daha çok Fenomenolojist ve İnterdisipliner yaklaşımın tercih edildiği Amerikan üniversitelerinin akademik kadro çeşitliliği ve başta İngilizce olmak üzere farklı dillerdeki yayın yelpazesinin genişliği ve son yıllarda yeni bir durum olan sosyal medyaya açık akademik faaliyetler ABD’nin İslam çalışmaları alanındaki etkinliğini giderek arttırmaktadır. Geçmişte İslam çalışmalarında öncü rolü oynayan İngiltere, Fransa, Almanya ve Hollanda gibi ülkelerde öteden beri oryantalist eğilimi temsil eden bu tür çalışmalar günümüz ABD üniversitelerinde interdisipliner ve multidisipliner bir format kazarak devam etmektedir. ABD’deki İslam çalışmaları üzerinde yoğunlaşan akademik çalışmalara göre İslam çalışmalarına yön veren en önemli etken oryantalist eğilimlerdir. Bunun yanında 11 Eylül olaylarının sonucunda da artan bir ilgiden söz etmek gerekmektedir. Bu ilgi sadece alanda yeni istihdam imkânlarının oluşmasına değil aynı zamanda araştırmacı sayısının da artmasına neden olmuştur. Çalışmamın ikinci kısmını oluşturan ABD üniversitelerindeki İslam felsefesi çalışmalarının genel durumuna bakılacak olursa bu çalışmaların sosyoloji, antropoloji ve kültür çalışmaları gibi alanlarda görülen çeşitliliğe de sahip olduğunu söylemek oldukça zordur. ABD üniversitelerindeki İslam felsefesi çalışmaları İslam çalışmaları genel çatısı altında sürdürülmektedir. Bu alandaki çalışmalar başlarda daha çok oryantalist eğilimi temsil eden Philip Hittî, Leo Strauss, Muhsin Mehdî, Fazlurrahmân, İsmâil Râci Fârukî, Mâcid Haddûrî, Moshe Pearlmann, gibi önemli isimler tarafından sürdürülmekteydi. Günümüzde Charles Butterworth, Seyyid Hüseyin Nasr, Oliver Leaman, Dimitri Gutas, Robert Wisnovsky, Frank Griffel, John Walbridge ve daha birçok isim yeni eğilimin temsilcileri olarak alanla ilgili çalışmalarını sürdürmektedir. Bu araştırmacılar, Amerikan akademik siteminin bir sonucu olarak sadece İslam felsefesi değil aynı zamanda İslam bilim tarihi, İslam tarihi ve medeniyeti, İslam ve Batı vb. alanlarda da yayınlar yapmakta ve İslam çalışmalarının sürdürüldüğü çeşitli üniversitelerde dersler vermekte ve lisansüstü seviyede öğrenciler yetiştirmektedir. Bu noktadan hareketle diyebiliriz ki İslam felsefesi çalışmaları ise diğer İslam çalışmalarına kıyasla daha da zayıftır. Bu durumun sebeplerini şu şekilde açıklamak mümkündür:1-Amerikan devlet felsefesinin temel ilkesi olan bilgi-güç hedefi ve alanın politik çıkarlarıyla ilişkisinin zayıflığı. Bilimlerle kurulan bu politik çıkar ilişkisi Post-Oryantalist eğilimin arka planını da oluşturmaktadır. 2-Amerikan Üniversitelerinde fenomenolojist yönteme olan ilginin artması ve Amerikan yükseköğretim sisteminde hâkim olan kozmopolitanizm ve interdisiplinerci yaklaşımlar.3-Amerikan üniversitelerindeki Yakın Doğu, Ortadoğu ve İslam Çalışmalarında İslam felsefesi dersleri felsefenin ya da felsefe tarihinin bir parçası olarak müfredatta yer alması. Amerikan üniversitelerinde standart müfredat sistemi yaygın olmadığından İslam felsefesi ile ilgili dersler bölümden daha çok ders veren hocanın ilgisine ve isteğine bağlı olarak verilmektedir.4-Kıta Avrupası’nda görülen katı oryantalist eğilimlerin nisbeten azlığı ve ABD devlet politikalarının gereği olarak şekillenen havuz usulü müfredat.5-Bazı İslam felsefesi uzmanlarının alanı terk ederek daha çok aktüel tartışmalara yönelmesi ve daha çok Müslümanların geri kalmışlığı sorunundan hareketle üretilen problemlere odaklanması. Son olarak İslam felsefesi çalışmaları Müslümanların genelinin ilgilendiği bir disiplin olmadığı için üniversite dışında İslam felsefesi çalışmalarının yürütüldüğü kurumsal yapılar ABD’de de henüz teşekkül etmemiştir. Bazı bölümlerde İslam Felsefesi İslam düşüncesi tarihinin bir alt dalı olarak varlığını sürdürmektedir. Ancak İslam felsefesi müstakil bir alan olarak kendisine henüz ABD üniversitelerinde yer bulamamıştır. USA’da artan İslam çalışmalarının yeterli düzeyde olmasa da dünyadaki islam çalışmalarına yön verebilecek noktaya ulaştığını söylemek mümkündür. (shrink)

One of the most extensive yet least conclusive methodological debates within religious studies revolves around the question of what, precisely, the phenomenology of religion is and what contribution it can make to the study of religion. I do not intend to answer this important question here. To do so satisfactorily would require a range of historical, philosophical and methodological inquiry which would go quite beyond the bounds of a single article. My intention in this paper is, by comparison, unambitious. It (...) is to take one view of what phenomenology of religion is and to consider an area outside that usually explored by students of religion which can, nonetheless, shed some light on how religions might be studied in a way which is in accordance with the phenomenology of religion so understood. What follows will offer an answer to the question of what contribution one particular understanding of phenomenology might make to the study of religion, but no attempt will be made to establish whether or not this particular understanding ought to be regarded as normative. (shrink)

The 65th year of a scholar who has devoted 40 years to editing and elucidating Robert Grosseteste provides us with a collection of essays. Not surprisingly, they emanate from colleagues and former students of Richard Dales and reflect his interest, among other concerns, in Grosseteste's aspectus et affectus - range of vision and disposition of mind - those twin peaks with which the 13th century thinker helped to get Christian thought through Aristotle without mutual destruction.

La réception tardive de l'oeuvre de Ernst Troeltsch en France nous a privés d'une analyse du christianisme originale et féconde. Elle nuance et enrichit ce que nous savons, au travers de la réflexion wébérienne notamment, des relations de la religion chrétienne à la modernité. Contre les interprétations usuelles qui datent l'émergence de cette dernière de la Renaissance et de la Réforme, Troeltsch insiste sur la centralité des Lumières comme marquant la fin de la civilisation ecclésiastique ; c'es l'évanouissement de la (...) référence structurante à l'ordre divin qui inau­gure selon lui l'entrée dans le monde moderne. Sur la base de ce constat, il s'agit pour Troeltsch de trouver une définition du christianisme qui soit en adéquation avec les conditions de l'existence moderne. Dans son ouvrage datant de 1912, « Les doctrines sociales des Églises et groupes chrétiens », il examine les types « Église », « secte » et « mystique » pré­sents depuis les origines évangéliques, circonscrivant trois modes socio­logiques et éthiques qu'il confronte à la modernité. Aucun n'est seul adéquat. Pour durer, le christianisme devra, selon Troeltsch, renoncer à la réalisation d'un programme éthique d'essence religieuse au sein du monde et accepter le cantonnement de la foi dans l'intimité des cons­ciences, tout en s'articulant à des réalités socio-culturelles à l'échelle de tous dont les formes et les transformations internes sont toujours à repenser.The delayed reception of the work of Ernst Troeltsch in France deprived us of an analysis of an original and fertile Christianity. It nuances and enriches what we know, especially through a Weberian reflection, about the relations of the Christian religion and modernity. Against the customary interpretations that date the emergence of the latter from the Renaissance and the Reformation, Troeltsch insists on the centrality of the Enlightenment as marking the end of an ecclesiastical civilization. It is the disappearance of the structuring reference to the divine order that inaugurated, according to him, the entrance to the modern world. On the basis of this observation, Troeltsch is interested in finding a definition of Christianity that would be in harmony with the conditions of modern existence. In his work dating from 1912, "The social doctrines of the Churches and Christian groups ", he examines the categories "Church", "sect", and "mystic" that were present evangelical times, circumscribing three sociological and ethical modes, which he confronts with modernity. No single one is adequate. In order to endure, Christian­ity should, according to Troeltsch, renounce the attempt to set up an ethical program of a religious essence in the heart of the world and accept the establishment of a faith in the intimacy of consciences, all the while adapting its« to socia-cultural realities applicable to everyone, of which the forms and internal transformations are always to be re-thought. (shrink)

Stiff Person Syndrome is a rare autoimmune disorder associated with antibodies against glutamic acid decarboxylase, the key enzyme in γ -aminobutyric acid synthesis. In order to investigate the role of cerebral benzodiazepinereceptor binding in SPS, we performed [ 11 C]flumazenil positron emission tomography in a female patient with SPS compared to nine healthy controls. FMZ is a radioligand to the postsynaptic central benzodiazepine receptor which is co-localized with the GABA-A receptor. In the SPS patient, we found a global reduction of (...) cortical FMZ binding. In addition, distinct local clusters of reduced radiotracer binding were observed. These data provide first in vivo evidence for a reduced postsynaptic GABA-A receptor availability which may reflect the loss of GABAergic neuronal inhibition in SPS. (shrink)

Galileo's Error (Goff, 2019) leaves important questions unasked and hence unanswered. I focus on two of these: the question of what a theory of consciousness is supposed to accomplish, and the question of what the materialismâ–“dualismâ–“panpsychism debate is actually about.

La posibilidad de sentar las bases para una psicología platónica de la acción puede ser abordada desde la perspectiva de la conexión entre la doctrina del alma tripartita de República y la psicología del placer del Filebo. A la luz de dicha conexión, la noción del alma como fuente del deseo se constituye en factor determinante de nuestro carácter personal y nuestra forma de actuar, lo que hace posible construir una tipología de hombre basada en la primacía de una parte (...) de su alma y en su preferencia por cierta clase de placer. Palabras clave: Platón; Psicología; Placer; Alma; Deseo; AcciónThe possibility of laying the foundations of a Platonic psychology of action can be tackled from the connection between Republic’s tripartite soul doctrine and Philebus’ psychology of pleasure. In the light of this connection, the notion of soul as the source of desire is a determining factor of our personal character and the way we act. This makes it possible to construct a typology of man based upon the primacy of one part of his soul and his preference for a certain kind of pleasure. Keywords: Plato; Psychology; Pleasure; Soul; Desire; Action. (shrink)